GHRP-2 is a non-glycosylated polypeptide chain containing six amino acids, with the sequence D-Ala-D-(β-naphthyl)-Ala-Ala-Trp-D-Phe-Lys-NH2 and molecular mass of 817.9749 g/mol. It is also termed “the hunger hormone.” GHRP-2 is associated with GHS(s) was discovered in the 1980s and studied considerably for their effects on GH release. Ghrelin, a newly discovered peptide, regulates the growth hormone release.
GHRP-2 (Growth Hormone Releasing Peptide – 2) is an integral part of the growth hormone secretagogue that helps to increase GH secretion by 7-15 times and boosts appetite. GHRP-2 can revive the release of IGF-1, and GH increases the bodyweight of various animal species. The skeletal muscle growth is directly proportional to feed conversion efficiency, daily gain, and meat percentage of the carcass.
GHRP-2 acts functionally different when compared to GHRH. GHRP-2 fits perfectly to examine the ghrelin effects on human eating behavior. Ghrelin, the endogenous ligand, helps to balance energy levels. They also help to balance over and under-nutritional deficiencies. To cover up this deficiency, you can visit biotechpeptides.com and find the best medications for your well-being.
GHRP-2 Mechanism
GHRP-2 mechanism takes place in two ways – At first, it supplements the natural growth hormone releasing signal that results in growth hormone secretion. Secondly, it represses somatostatin, a growth hormone inhibiting hormone (GHIH). Thus, it helps to reduce natural hormone growth production and keeps control over the activity of somatostatin. Ghrelin activates in the gastrointestinal system that leads to an increase in hormones and appetite.
With synthetic hGH administration, it is nearly impossible to cease natural growth hormone production. GHRP-2 allows the release of growth hormones similar to that of the natural growth hormone secretion process. This mechanism helps to prevent some side effects considering restricting activity related to natural growth hormone production.
Usage
GHRP-2 works wonders to grow muscle mass, reduce body fats, improves flexibility and joint health. More uses are mentioned below-
- It provides fast recovery against injuries and training.
- It enhances your sleep patterns, diminishes aging effects, and promotes overall well-being.
- IGF-1 production helps to improve the lean body, fastens muscle tissue growth, and decreases body fat.
- GHRP-2 strengthens the body and contributes to highlight athletic performance, accelerate muscle tissue growth, and reduce age-related decline.
- It also helps to decrease powerful hunger side effects related to GHRP-6.
- GHRP-2 helps to enhance sleep patterns.
- Nurture collagen production and healthier skin.
- Reduce the risk of cardiovascular disease.
- Boost up the immune system.
- Generate desire for sex through hypothalamic stimulation.
Possible Side-Effects of GHRP-2
Every treatment comes with some side effects. Some of them are mentioned below:
- Tiredness and lethargic behavior
- Mitigates insulin sensitivity
- Skin irritation at the injection site
- Carpal tunnel syndrome
- Increases hunger but not substantially
- Overdose can lead to numbness in the hands and feet.
Differences between GHRP-2 and GHRP-6
Both GHRP-2 and GHRP-6 have similar effects. But somehow, they vary from each other. GHRP-2 peptide doesn’t evoke as much hunger as GHRP-6 does. On the contrary, higher doses of GHRP-2 lead to an increase in cortisol and prolactin production.
Another big difference between both peptides is that GHRP-2 releases more growth hormones as compared to GHRP-6. Moreover, GHRP-2 helps to improve calcium levels in the body. Therefore, it also helps to meet catabolic deficiencies. GHRP-6 is not a suitable choice for a healthy composition of your body.
How GHRP-2 peptide proves to be beneficial?
GHRP-2 peptide has the following possible benefits on a commercial level –
Heart Protection
It has been observed that GHRP-2, GHRP-1, and GHRP – 6 can help to minimize apoptosis or programmed cell death with the help of cardiac cells. These peptides have a deep association with a specific receptor that helps to avoid dysfunction by creating novel pathways for newer drugs.
Improved Muscle Structure
GHRP-2 peptide allows enhancing muscle protein deposition with the help of the growth hormone activation process and insulin. Improved protein synthesis and decreased degradation increase body mass to make lean bodies look attractive.
Enhance Appetite
This peptide helps to increase hunger which automatically stimulates appetite. It is highly beneficial for chronically ill patients and results in generating long-term outcomes.
Strengthens the Immunity System
The thymus organ plays an integral role in boosting the human immune system. It protects and matures some cells specially the T Lymphocytes. The efficacy of the thymus reduces with age and leads to cause illnesses such as the inability to combat cancer, normal tissue functions, and so on.
T Lymphocytes can fight complex infections. GHRP-2 peptides help to rejuvenate the thymus. As a result, the general immunity system stays protected.
Avoid Unwanted Pain
GHRP-2 peptide provides relief from pain before the repair of damaged tissues. This peptide itself is an opioid receptor that binds to the receptors responsible for addiction, sedation, and pain relief.
Improves Sleep Pattern
The peptide enhances stage 3 and 4 sleep cycles by 50% whereas influences the REM sleep duration by 20%. A better sleep cycle results in improved cognitive function, blood pressure, energy, and healing levels. These are more focused on the adult population as stress harms the individuals with the increasing age.
Dosage
Amount: 150mcg – 300 mcg (varies from individual to individual)
Frequency: one to three times per day
For strengthening your body, experts recommend a dosage amount of 0.3 mg (3 times a day)
For reducing aging effects, 150mcg must be taken daily before going to bed.
For outstanding results, it is advisable not to eat one hour before and after the GHRP-2 administration. It has been proved that a subcutaneous infusion of GHRP-2 for 270 is considered safe. No side effects were reported during the 30-day infusion period.
GHRP-2 and its clinical uses
GHRP-2 has significance when used for clinical purposes. It is used as a diagnostic agent for the treatment of growth hormone deficiency (GHD) with the help of a single dose formation. To assess problems like GHD and short stature (pituitary dwarfism), phase II-based clinical trials have also taken place.
In GHRP-2, humans with GHD have less chance to increase plasma GH levels when compared to healthy individuals. Hence, this peptide has not been promoted for GHD treatment. GHRP-2, like ghrelin, has turned out to be clinically helpful to understand the complexity of food intake behavior regulation in human beings.
